Biomedicina

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Navegando Biomedicina por Autor "LUANA CARDENAS DE AQUINO"

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    ACIDENTES OFÍDICOS E PLANTAS MEDICINAIS: UMA REVISÃO ABRANGENTE DA LITERATURA
    (2024-12-12) LUANA CARDENAS DE AQUINO; MIQUÉIAS HENRIQUE PAZINI GARCIA
    In Brazil, the direct and daily contact with nature by individuals from isolated communities implies a higher probability of snakebite accidents, mainly caused by snakes of the genera Bothrops sp (“jararaca”), Crotalus sp (“rattlesnake”), Lachesis sp (“bushmaster”), and Micrurus sp (“true coral snake”). This suggests the need for developing new methods and strategies useful in the therapeutic management of snakebite accidents, especially for these individuals. Various medicinal plants from Brazilian flora possess antivenom properties and are used by individuals from isolated communities as antidotes for snakebites. However, some of these antidotes do not have their composition disclosed by users, and data on their therapeutic efficacy and safety are scarce in the literature.The objective of this study was to gather data through a bibliographic review and propose a comparison between common and scientific knowledge regarding the potential antivenom properties of these plants so they can be used as complementary treatments for snakebite accidents. To achieve this, an electronic search was conducted in the following databases: Scientific Electronic Library Online (SciELO), Medline, PubMed, and ResearchGate. The descriptors used for the literature search were: “Snakebite accidents,” “antivenoms,” “medicinal plants,” “secondary metabolites,” “traditional knowledge,” and their respective equivalents in English.To ensure the scientific quality of the present work, only publications indexed in the mentioned databases were included. Articles, theses, dissertations, and monographs that had titles, abstracts, and scientific content relevant to the theme of this study were included (even if published more than 10 years ago). Otherwise, they were excluded. Different plants, native to Brazil or not, have shown effectiveness in the palliative treatment of snakebite symptoms. Among these, Bellucia dichotoma, Marsypianthes chamaedrys, Serjania erecta, and Anacardium humile stand out for their antivenom capabilities. Thus, it is concluded that the medicinal plants presented in this study can be considered a safe and beneficial therapeutic alternative, with no significant adverse effects. Furthermore, the inclusion of medicinal plants in snakebite treatment can represent an advancement in palliative therapy based on natural compounds, providing an accessible and effective approach to this public health issue.