Biomedicina
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Item PODEM AS PLANTAS MEDICINAIS E/OU SEUS CONSTITUINTES REPRESENTAREM UMA OPÇÃO TERAPÊUTICA NO TRATAMENTO DOTRANSTORNO DE DÉFICIT DE ATENÇÃO E HIPERATIVIDADE? UMA REVISÃO ABRANGENTE DA LITERATURA(2024-12-11) EDUARDO JUNIO DURAN; GIULIANA OKAJIMA COSTA LEMESAttention Deficit Hyperactivity Disorder (ADHD) is a neurobiological disorder that affects both children and adults, characterized by symptoms such as inattention, hyperactivity and impulsivity. The decrease in basal catecholamine levels in the prefrontal cortex is directly related to ADHD symptoms. Psychostimulant drugs have beneficial effects in the treatment of ADHD, however, these drugs can often cause serious adverse effects that can outweigh their therapeutic effects. The amount of research into medicinal plants, aimed at discovering new active ingredients of natural origin that represent an effective and safer option in the treatment of ADHD, has increased substantially in recent years. The objective of the present work was to carry out a comprehensive review of the literature with the purpose of describing the main medicinal plants useful in the treatment of ADHD and their main therapeutic implications. The review was carried out based on U.S. PubMed. National Library of Medicine (https://pubmed.ncbi.nlm.nih.gov/) using pre-defined keywords: “Natural compounds”, “Medicinal plants”, “Attention deficit/hyperactivity disorder”, “Secondary metabolites”, “Psychostimulants”. To ensure the good quality of this work, only publications indexed in the aforementioned database were included. In this way, articles that present a title, abstract and scientific content that fit the theme of this work were included, otherwise they were rejected.